Overview
SCIENTIFIC SCORE
Questionable
Based on 23 Researches
6.6
USERS' SCORE
Moderately Good
Based on 68 Reviews
7.5
Supplement Facts
Serving Size: 2 Tablets
Amount Per Serving
%DV
Magnesium (from 2,000 mg magnesium lysinate glycinate chelate) (Albion®)
200 mg
48%
Top Medical Research Studies
9
We explored the potential of magnesium implantation as a new approach to combat heart attacks, specifically myocardial infarction (MI). Our research centered on using magnesium slices implanted under the skin of rats to generate hydrogen gas continuously. This method could ensure a greater and longer-lasting concentration of hydrogen directly reaching the heart, which is crucial for its therapeutic effects.
Through our study, we measured how effectively the magnesium produced hydrogen and evaluated its safety. The results were promising; we observed that magnesium implantation not only improved cardiac function in rats suffering from MI, but also played a role in eliminating harmful free radicals from mitochondrial dysfunction. Furthermore, it helped reduce cell death in heart muscle cells, which is a common consequence of heart attacks.
Compared to traditional hydrogen inhalation, which has limitations in delivering sufficient doses over time, magnesium implantation proved to be a superior method. Overall, our findings pave the way for innovative treatments that could enhance recovery after heart attacks by harnessing the unique properties of magnesium for hydrogen production.
Through our study, we measured how effectively the magnesium produced hydrogen and evaluated its safety. The results were promising; we observed that magnesium implantation not only improved cardiac function in rats suffering from MI, but also played a role in eliminating harmful free radicals from mitochondrial dysfunction. Furthermore, it helped reduce cell death in heart muscle cells, which is a common consequence of heart attacks.
Compared to traditional hydrogen inhalation, which has limitations in delivering sufficient doses over time, magnesium implantation proved to be a superior method. Overall, our findings pave the way for innovative treatments that could enhance recovery after heart attacks by harnessing the unique properties of magnesium for hydrogen production.
Read More
8
We examined whether serum magnesium levels at admission could predict in-hospital outcomes for patients experiencing a heart attack.
In our study of 259 acute myocardial infarction patients, those with lower magnesium levels (below 1.82 mg/dl) faced significantly higher risks of complications, including arrhythmias and even death, compared to those with healthier levels.
Our findings suggest that maintaining adequate magnesium levels is essential for better health outcomes after a heart attack.
In our study of 259 acute myocardial infarction patients, those with lower magnesium levels (below 1.82 mg/dl) faced significantly higher risks of complications, including arrhythmias and even death, compared to those with healthier levels.
Our findings suggest that maintaining adequate magnesium levels is essential for better health outcomes after a heart attack.
Read More
5
OCT and angiography show comparable effectiveness
We examined how two guidance methods—optical coherence tomography (OCT) and angiography—perform during magnesium bioresorbable scaffold (MBRS) implantation in patients recovering from a non-ST-elevation heart attack.
With 75 participants, our study revealed that both techniques resulted in comparable healing patterns after six months. Though OCT-guided intervention showed slightly better outcomes in certain technical measures, neither approach demonstrated a significant advantage in overall heart healing.
Thus, for NSTEMI patients, choosing between OCT and angiography for MBRS placement may depend on other factors, as both methods appear effective.
With 75 participants, our study revealed that both techniques resulted in comparable healing patterns after six months. Though OCT-guided intervention showed slightly better outcomes in certain technical measures, neither approach demonstrated a significant advantage in overall heart healing.
Thus, for NSTEMI patients, choosing between OCT and angiography for MBRS placement may depend on other factors, as both methods appear effective.
Read More
Most Useful Reviews
9
Supports heart function
138 people found this helpful
Following a heart attack, magnesium has been very beneficial for my body in maintaining normal cardiovascular function. I now take this supplement regularly to prevent future issues.
Read More
9
Palpitations resolved
21 people found this helpful
I started taking magnesium to address heart palpitations caused by birth control pills. Since switching to this absorbed form, I've not experienced any incidents. Truly fantastic!
Read More
9
Palpitations eliminated
20 people found this helpful
After researching my symptoms, I realised I had a magnesium deficiency. After starting Doctor's Best chelated magnesium, my chest tightness, leg cramps, and insomnia vanished within two weeks. Even my 84-year-old mother has benefited from it, eliminating her night palpitations.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 23 Researches
6.6
- All Researches
9
We explored the potential of magnesium implantation as a new approach to combat heart attacks, specifically myocardial infarction (MI). Our research centered on using magnesium slices implanted under the skin of rats to generate hydrogen gas continuously. This method could ensure a greater and longer-lasting concentration of hydrogen directly reaching the heart, which is crucial for its therapeutic effects.
Through our study, we measured how effectively the magnesium produced hydrogen and evaluated its safety. The results were promising; we observed that magnesium implantation not only improved cardiac function in rats suffering from MI, but also played a role in eliminating harmful free radicals from mitochondrial dysfunction. Furthermore, it helped reduce cell death in heart muscle cells, which is a common consequence of heart attacks.
Compared to traditional hydrogen inhalation, which has limitations in delivering sufficient doses over time, magnesium implantation proved to be a superior method. Overall, our findings pave the way for innovative treatments that could enhance recovery after heart attacks by harnessing the unique properties of magnesium for hydrogen production.
Through our study, we measured how effectively the magnesium produced hydrogen and evaluated its safety. The results were promising; we observed that magnesium implantation not only improved cardiac function in rats suffering from MI, but also played a role in eliminating harmful free radicals from mitochondrial dysfunction. Furthermore, it helped reduce cell death in heart muscle cells, which is a common consequence of heart attacks.
Compared to traditional hydrogen inhalation, which has limitations in delivering sufficient doses over time, magnesium implantation proved to be a superior method. Overall, our findings pave the way for innovative treatments that could enhance recovery after heart attacks by harnessing the unique properties of magnesium for hydrogen production.
Read More
9
Magnesium scaffolds improve heart attack outcomes
We examined the performance of two types of bioresorbable scaffolds in patients experiencing acute coronary syndrome (ACS) - a common and serious manifestation of heart disease. Specifically, we compared the effectiveness of magnesium-based scaffolds, known as Magmaris, with the earlier polymer scaffolds called Absorb.
Our study included 193 patients using Magmaris and 160 patients using Absorb, all treated in similar clinical settings. Over the course of one year, we monitored their health outcomes, particularly focusing on serious issues like cardiac death, heart attacks, and instances of scaffold thrombosis.
Surprisingly, we found that patients with Magmaris had significantly better outcomes than those with Absorb. Specifically, the rates of primary complications and target lesion failures were notably lower with Magmaris. We noted a concerning trend with Absorb, where patients experienced a higher rate of scaffold thrombosis.
Overall, our findings suggest that magnesium-based scaffolds could provide a safer and more effective option for patients undergoing treatment for heart attacks compared to their polymer counterparts.
Our study included 193 patients using Magmaris and 160 patients using Absorb, all treated in similar clinical settings. Over the course of one year, we monitored their health outcomes, particularly focusing on serious issues like cardiac death, heart attacks, and instances of scaffold thrombosis.
Surprisingly, we found that patients with Magmaris had significantly better outcomes than those with Absorb. Specifically, the rates of primary complications and target lesion failures were notably lower with Magmaris. We noted a concerning trend with Absorb, where patients experienced a higher rate of scaffold thrombosis.
Overall, our findings suggest that magnesium-based scaffolds could provide a safer and more effective option for patients undergoing treatment for heart attacks compared to their polymer counterparts.
Read More
8
Magnesium enhances heart attack recovery
We explored an innovative approach to treating myocardial infarction (MI) by using a special composite hydrogel that incorporates magnesium-modified black phosphorus nanosheets. This treatment aims to address the significant changes in the heart's environment after a heart attack, which are usually detrimental to recovery.
The research involved creating a hydrogel scaffold that allows for the gradual release of these magnesium-enhanced nanosheets directly at the site of the infarct. This is particularly important because sustained release helps to manage oxidative stress and inflammation, both common issues following a heart attack.
We observed that the black phosphorus nanosheets have a high reactivity with reactive oxygen species (ROS), which helps reduce oxidative stress and inflammation in the heart. Additionally, the magnesium contributes to promoting blood vessel growth, or angiogenesis, which is crucial for long-term heart function after an MI.
Overall, the findings of this study suggest that the combination of these elements in the hydrogel can effectively block further damage from the heart attack and improve recovery outcomes, signaling a promising avenue for heart attack treatments in the future.
The research involved creating a hydrogel scaffold that allows for the gradual release of these magnesium-enhanced nanosheets directly at the site of the infarct. This is particularly important because sustained release helps to manage oxidative stress and inflammation, both common issues following a heart attack.
We observed that the black phosphorus nanosheets have a high reactivity with reactive oxygen species (ROS), which helps reduce oxidative stress and inflammation in the heart. Additionally, the magnesium contributes to promoting blood vessel growth, or angiogenesis, which is crucial for long-term heart function after an MI.
Overall, the findings of this study suggest that the combination of these elements in the hydrogel can effectively block further damage from the heart attack and improve recovery outcomes, signaling a promising avenue for heart attack treatments in the future.
Read More
8
In our investigation, we set out to understand how magnesium lithospermate B (MLB) can aid heart repair following a heart attack. We used a mouse model with surgically induced myocardial infarction (MI) and categorized the mice into five groups, including those treated with MLB and human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs). By comparing different treatments, we evaluated the heart's recovery over four weeks through echocardiography and histochemical staining.
Our findings revealed that MLB significantly enhances the function of hiPSC-CMs, helping to repair the damaged heart muscle. This improvement happens by boosting the function of endothelial cells—important for blood vessel health—through a specific signaling pathway. Additionally, MLB decreases apoptosis, or cell death, in hiPSC-CMs by activating another pathway, which further supports heart recovery.
Overall, our work underscores the role of MLB in improving heart repair after a heart attack. While it was tested in tandem with hiPSC-CMs, which makes it an interesting combination for treatment strategies, it's clear that the integration of MLB can potentially enhance cardiac recovery mechanisms effectively.
Our findings revealed that MLB significantly enhances the function of hiPSC-CMs, helping to repair the damaged heart muscle. This improvement happens by boosting the function of endothelial cells—important for blood vessel health—through a specific signaling pathway. Additionally, MLB decreases apoptosis, or cell death, in hiPSC-CMs by activating another pathway, which further supports heart recovery.
Overall, our work underscores the role of MLB in improving heart repair after a heart attack. While it was tested in tandem with hiPSC-CMs, which makes it an interesting combination for treatment strategies, it's clear that the integration of MLB can potentially enhance cardiac recovery mechanisms effectively.
Read More
8
We explored how serum magnesium levels at the time of hospital admission affect the long-term health of patients experiencing a non-ST-elevation myocardial infarction (NSTEMI). In our analysis of data from over 4,500 patients, we focused on the differences between those with low serum magnesium levels—defined as below 1.9 mg/dL—and those with normal or higher levels.
Our findings indicate that patients with low magnesium levels were older, had more health complications like diabetes and hypertension, and faced a higher long-term risk of mortality. Specifically, we observed that 34% of patients with low magnesium levels died within four years, compared to 22% of those with adequate levels.
Importantly, even after adjusting for factors such as sex, existing health conditions, and interventions received during hospitalization, low serum magnesium levels still correlated with a significantly increased risk of death by 24%. While we revealed that low magnesium levels could be a concerning signal for NSTEMI patients, we did not assess the effects of magnesium treatment directly in this study.
Overall, this research brings to light the potential importance of monitoring magnesium levels in the clinical setting, highlighting how they may relate to long-term outcomes for heart attack patients.
Our findings indicate that patients with low magnesium levels were older, had more health complications like diabetes and hypertension, and faced a higher long-term risk of mortality. Specifically, we observed that 34% of patients with low magnesium levels died within four years, compared to 22% of those with adequate levels.
Importantly, even after adjusting for factors such as sex, existing health conditions, and interventions received during hospitalization, low serum magnesium levels still correlated with a significantly increased risk of death by 24%. While we revealed that low magnesium levels could be a concerning signal for NSTEMI patients, we did not assess the effects of magnesium treatment directly in this study.
Overall, this research brings to light the potential importance of monitoring magnesium levels in the clinical setting, highlighting how they may relate to long-term outcomes for heart attack patients.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 68 Reviews
7.5
- All Reviews
- Positive Reviews
- Negative Reviews
9
Supports heart function
138 people found this helpful
Following a heart attack, magnesium has been very beneficial for my body in maintaining normal cardiovascular function. I now take this supplement regularly to prevent future issues.
Read More
9
Palpitations resolved
21 people found this helpful
I started taking magnesium to address heart palpitations caused by birth control pills. Since switching to this absorbed form, I've not experienced any incidents. Truly fantastic!
Read More
9
Palpitations eliminated
20 people found this helpful
After researching my symptoms, I realised I had a magnesium deficiency. After starting Doctor's Best chelated magnesium, my chest tightness, leg cramps, and insomnia vanished within two weeks. Even my 84-year-old mother has benefited from it, eliminating her night palpitations.
Read More
9
Stopped palpitations
15 people found this helpful
It worked! My palpitation was terrible, and I questioned whether it was due to menopause or heart disease. After drinking this 4-6 times a day, I stopped immediately! I also consume protein and various vitamins, but magnesium was what I needed.
Read More
9
Extrasystole eliminated
11 people found this helpful
My extrasystole was awful, and it exhausted me daily. After trying magnesium from iHerb and taking one tablet twice daily, I noticed my heart no longer felt off rhythm. I returned to this dose after feeling dizzy with higher doses. When I paused, I felt my heart acting up again. I’ll stick to my dosage continuously.
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Frequently Asked Questions
9
Positive heart stabilisation
2 people found this helpful
I am very satisfied with this supplement. For over a decade, I have suffered from arrhythmia and dyspnea, often relying on magnesium preparations. Unlike many pharmacy products that disappointed me, Magnesium from Doctor Best has improved my condition significantly. I noticed its effects after about a week, and my heart rate remains stable even with weather changes. This is a tremendous benefit for me, and I plan to continue taking the supplement.
9
Palpitations eliminated
20 people found this helpful
After researching my symptoms, I realised I had a magnesium deficiency. After starting Doctor's Best chelated magnesium, my chest tightness, leg cramps, and insomnia vanished within two weeks. Even my 84-year-old mother has benefited from it, eliminating her night palpitations.
9
Atrial fibrillation aid
4 people found this helpful
I have successfully used Doctor's Best magnesium to manage my atrial fibrillation. I attribute my sustained arrhythmia-free period to it, as it is the most reliable glycinated product I’ve encountered for heart rhythm support.
9
Supports heart function
138 people found this helpful
Following a heart attack, magnesium has been very beneficial for my body in maintaining normal cardiovascular function. I now take this supplement regularly to prevent future issues.
9
Palpitations resolved
21 people found this helpful
I started taking magnesium to address heart palpitations caused by birth control pills. Since switching to this absorbed form, I've not experienced any incidents. Truly fantastic!
9
Migraine relief
1 people found this helpful
I've been taking magnesium for a month, and I've already noticed improvements. My insomnia has disappeared, and my migraines are gone. After workouts, muscle pain subsides faster. No digestive issues or headaches for me! The tablets are large but can be broken easily.
0
Counterproductive supplement
5 people found this helpful
I suffer from heart palpitations, and after trying this supplement twice, I experienced worse palpitations. It does not suit me.
9
Stopped palpitations
15 people found this helpful
It worked! My palpitation was terrible, and I questioned whether it was due to menopause or heart disease. After drinking this 4-6 times a day, I stopped immediately! I also consume protein and various vitamins, but magnesium was what I needed.
7
We investigated the role of magnesium in the development of contrast-induced nephropathy (CIN) following primary percutaneous coronary intervention (pPCI) in patients suffering from ST-Elevation Myocardial Infarction (STEMI). In our study involving over 2,300 STEMI patients, we found that 30% developed CIN after their procedure. Analyzing the magnesium levels present at admission, we observed that those who experienced CIN had significantly lower magnesium levels compared to those who didn't.
Our findings revealed that magnesium levels below 2.03 mg/dL were linked to an increased risk of developing CIN, alongside other factors like age over 68 years and reduced left ventricular function. We identified this magnesium cutoff through rigorous analysis, demonstrating that low levels of this mineral can be a significant indicator of risk in heart attack patients following a procedure. This insight emphasizes the potential importance of monitoring magnesium levels to help predict and possibly prevent CIN in these vulnerable patients.
Our findings revealed that magnesium levels below 2.03 mg/dL were linked to an increased risk of developing CIN, alongside other factors like age over 68 years and reduced left ventricular function. We identified this magnesium cutoff through rigorous analysis, demonstrating that low levels of this mineral can be a significant indicator of risk in heart attack patients following a procedure. This insight emphasizes the potential importance of monitoring magnesium levels to help predict and possibly prevent CIN in these vulnerable patients.
7
We investigated how serum magnesium levels affect the risk of acute kidney injury (AKI) in patients who experienced ST segment elevation myocardial infarction (STEMI), a severe type of heart attack. In our study, we reviewed data from 1,219 patients, dividing them into two groups: those with hypomagnesemia (low magnesium levels) and those without. Hypomagnesemia was specifically defined as having a serum magnesium level of less than 0.75 mmol/L, a threshold that indicates deficiency.
Out of the participants, we found that 163 patients (about 13.4%) were hypomagnesemic, and alarmingly, 256 patients (21.0%) developed AKI during their hospital stay. The figures showed a significant disparity: AKI occurred in 31.9% of the hypomagnesemia group compared to 19.3% of those with normal magnesium levels, signaling a concerning association.
Our analysis indicated that hypomagnesemia is an independent risk factor for developing AKI, with a calculated odds ratio of 2.41. This suggests that patients with lower magnesium at admission face more than double the risk of experiencing kidney complications. These findings highlight the potential for magnesium interventions in heart attack recovery, suggesting that monitoring and managing magnesium levels could play a crucial role in improving patient outcomes and reducing the risk of kidney injury after a heart attack.
Out of the participants, we found that 163 patients (about 13.4%) were hypomagnesemic, and alarmingly, 256 patients (21.0%) developed AKI during their hospital stay. The figures showed a significant disparity: AKI occurred in 31.9% of the hypomagnesemia group compared to 19.3% of those with normal magnesium levels, signaling a concerning association.
Our analysis indicated that hypomagnesemia is an independent risk factor for developing AKI, with a calculated odds ratio of 2.41. This suggests that patients with lower magnesium at admission face more than double the risk of experiencing kidney complications. These findings highlight the potential for magnesium interventions in heart attack recovery, suggesting that monitoring and managing magnesium levels could play a crucial role in improving patient outcomes and reducing the risk of kidney injury after a heart attack.
7
We investigated how variations in serum magnesium levels might relate to in-hospital mortality for patients experiencing an acute myocardial infarction (AMI), commonly known as a heart attack. The research examined data from over 2,700 patients in intensive care, allowing us to analyze trends over time.
What we found was significant: elevated magnesium levels at ICU admission and changes in magnesium levels within the first 48 hours of ICU stay were associated with a higher risk of in-hospital mortality among these patients. In fact, 18.6% of the patients in our study did not survive their hospital stay.
This relationship remained consistent across different groups, regardless of age, gender, or health severity scores. It highlights the importance of closely monitoring magnesium levels during crucial treatment periods as it may provide insight that could help tailor treatments to improve patient outcomes.
However, we must note that while the study shows an association, it does not isolate the effects of magnesium treatment itself. This means we can't definitively say that magnesium treatment alone drastically alters mortality rates after a heart attack. Instead, the findings suggest magnesium monitoring is vital in intensive care settings.
What we found was significant: elevated magnesium levels at ICU admission and changes in magnesium levels within the first 48 hours of ICU stay were associated with a higher risk of in-hospital mortality among these patients. In fact, 18.6% of the patients in our study did not survive their hospital stay.
This relationship remained consistent across different groups, regardless of age, gender, or health severity scores. It highlights the importance of closely monitoring magnesium levels during crucial treatment periods as it may provide insight that could help tailor treatments to improve patient outcomes.
However, we must note that while the study shows an association, it does not isolate the effects of magnesium treatment itself. This means we can't definitively say that magnesium treatment alone drastically alters mortality rates after a heart attack. Instead, the findings suggest magnesium monitoring is vital in intensive care settings.
4
We aimed to explore the connection between serum magnesium levels and cardiac complications in patients who experienced heart attacks, specifically acute myocardial infarction. The study focused on 160 patients admitted to the Prince Faisal Bin Khalid Cardiac Center shortly after their symptoms began. We measured their serum magnesium levels on the first and fifth days of hospitalization.
Our findings revealed that over half of the patients had low magnesium levels upon admission. Notably, those with decreased magnesium were more likely to have diabetes, a history of diuretic use, and were medicated with beta-blockers, calcium channel blockers, and statins. Unfortunately, this group also experienced serious complications such as atrial fibrillation and cardiogenic shock more frequently.
Ultimately, lower magnesium levels were linked to poorer outcomes in these heart attack patients. This suggests that magnesium might play a significant role in the health status of individuals suffering from this critical condition, although the effectiveness of direct magnesium treatment remains unclear given the various medications and factors at play.
Our findings revealed that over half of the patients had low magnesium levels upon admission. Notably, those with decreased magnesium were more likely to have diabetes, a history of diuretic use, and were medicated with beta-blockers, calcium channel blockers, and statins. Unfortunately, this group also experienced serious complications such as atrial fibrillation and cardiogenic shock more frequently.
Ultimately, lower magnesium levels were linked to poorer outcomes in these heart attack patients. This suggests that magnesium might play a significant role in the health status of individuals suffering from this critical condition, although the effectiveness of direct magnesium treatment remains unclear given the various medications and factors at play.
8
Magnesium enhances heart attack recovery
We explored an innovative approach to treating myocardial infarction (MI) by using a special composite hydrogel that incorporates magnesium-modified black phosphorus nanosheets. This treatment aims to address the significant changes in the heart's environment after a heart attack, which are usually detrimental to recovery.
The research involved creating a hydrogel scaffold that allows for the gradual release of these magnesium-enhanced nanosheets directly at the site of the infarct. This is particularly important because sustained release helps to manage oxidative stress and inflammation, both common issues following a heart attack.
We observed that the black phosphorus nanosheets have a high reactivity with reactive oxygen species (ROS), which helps reduce oxidative stress and inflammation in the heart. Additionally, the magnesium contributes to promoting blood vessel growth, or angiogenesis, which is crucial for long-term heart function after an MI.
Overall, the findings of this study suggest that the combination of these elements in the hydrogel can effectively block further damage from the heart attack and improve recovery outcomes, signaling a promising avenue for heart attack treatments in the future.
The research involved creating a hydrogel scaffold that allows for the gradual release of these magnesium-enhanced nanosheets directly at the site of the infarct. This is particularly important because sustained release helps to manage oxidative stress and inflammation, both common issues following a heart attack.
We observed that the black phosphorus nanosheets have a high reactivity with reactive oxygen species (ROS), which helps reduce oxidative stress and inflammation in the heart. Additionally, the magnesium contributes to promoting blood vessel growth, or angiogenesis, which is crucial for long-term heart function after an MI.
Overall, the findings of this study suggest that the combination of these elements in the hydrogel can effectively block further damage from the heart attack and improve recovery outcomes, signaling a promising avenue for heart attack treatments in the future.
4
We evaluated how magnesium supplementation could influence heart attack outcomes based on a large-scale study involving 884 randomized controlled trials. This extensive analysis considered various micronutrients and their effects on heart health, focusing specifically on cardiovascular disease (CVD) risks. While some nutrients, like n-3 fatty acids and folic acid, showed promising reductions in heart attack risks, magnesium's isolated impact wasn't clearly established. It was examined alongside other treatments, preventing us from determining its specific effectiveness effectively.
Overall, the study indicates that while magnesium is one of many micronutrients considered for heart health, its direct role in heart attack prevention remains uncertain. We found that some micronutrients provide a considerable advantage for cardiometabolic health, while others, like β-carotene, may even pose risks. This underscores the need for further research to fully understand magnesium's benefits on heart attack risk, especially when included in broader dietary patterns.
Overall, the study indicates that while magnesium is one of many micronutrients considered for heart health, its direct role in heart attack prevention remains uncertain. We found that some micronutrients provide a considerable advantage for cardiometabolic health, while others, like β-carotene, may even pose risks. This underscores the need for further research to fully understand magnesium's benefits on heart attack risk, especially when included in broader dietary patterns.
8
Magnesium's potential heart benefits
We explored how magnesium intake may influence mortality risks in individuals who have suffered a heart attack, specifically myocardial infarction (MI). The study focused on 4,365 Dutch patients aged between 60 and 80 who had experienced an MI less than ten years before the study began.
By analyzing dietary data collected through a detailed food frequency questionnaire, we were able to assess the participants' magnesium intake and its association with cardiovascular disease (CVD) and all-cause mortality. Notably, we discovered that adequate magnesium intake could lower long-term mortality risks post-MI, particularly among patients using diuretics.
While our findings are promising, they also highlight the complexity of examining dietary influences on health outcomes amidst varying medical treatments. Overall, this research suggests that magnesium could play a beneficial role in recovery after heart attacks, warranting further investigation in diverse patient groups.
By analyzing dietary data collected through a detailed food frequency questionnaire, we were able to assess the participants' magnesium intake and its association with cardiovascular disease (CVD) and all-cause mortality. Notably, we discovered that adequate magnesium intake could lower long-term mortality risks post-MI, particularly among patients using diuretics.
While our findings are promising, they also highlight the complexity of examining dietary influences on health outcomes amidst varying medical treatments. Overall, this research suggests that magnesium could play a beneficial role in recovery after heart attacks, warranting further investigation in diverse patient groups.
References
- Demirtola Aİ, Mammadli A, Çiçek G. The Role of Magnesium Levels in the Progression of Contrast-Induced Nephropathy in Patients With STEMI Undergoing Primary PCI. Angiology. 2025. doi:10.1177/00033197251314629
- Jin Y, Lin Q, Wang D, Gong M, Huang W, et al. Hypomagnesemia is a Risk Factor for Acute Kidney Injury in Patients Admitted With ST-Segment Elevation Myocardial Infarction: A Retrospective Observational Study. J Ren Nutr. 2024. doi:10.1053/j.jrn.2024.12.006
- Naveen V, Rajesh Lenin R, Stanley LM, Kumar JS. Serum Magnesium Levels and QTc Interval Prolongation As Prognostic Markers in Acute Myocardial Infarction: A Randomized Controlled Study. Cureus. 2024;16:e66051. doi:10.7759/cureus.66051
- Zhuang J, Zhang Q, Wang H, Su PH, Chen PY. Association between short-term changes in serum magnesium and in-hospital mortality following acute myocardial infarction: a cohort study based on the MIMIC database. Magnes Res. 2024;37:45. doi:10.1684/mrh.2024.0517
- Zhang J, Sun D, Guo Y, Tong J, Liu Q, et al. Targeted delivery of black phosphorus nanosheets by ROS responsive complex hydrogel based on angiogenesis and antioxidant promotes myocardial infarction repair. J Nanobiotechnology. 2024;22:433. doi:10.1186/s12951-024-02685-0
- Wang B, Pan S, Nie C, Zou R, Liu J, et al. Magnesium implantation as a continuous hydrogen production generator for the treatment of myocardial infarction in rats. Sci Rep. 2024;14:10959. doi:10.1038/s41598-024-60609-2
- Fan C, Qin K, Iroegbu CD, Xiang K, Gong Y, et al. Magnesium lithospermate B enhances the potential of human-induced pluripotent stem cell-derived cardiomyocytes for myocardial repair. Chin Med J (Engl). 2024;137:1857. doi:10.1097/CM9.0000000000002867
- Segev A, Shechter M, Tsur AM, Belkin D, Cohen H, et al. Serum Magnesium Is Associated with Long-Term Survival of Non-ST-Elevation Myocardial Infarction Patients. Nutrients. 2023;15. doi:10.3390/nu15194299
- Włodarczak A, Rola P, Barycki M, Furtan Ł, Łanocha M, et al. Mid-term safety and efficacy of magnesium bioresorbable vascular scaffolds - magmaris in diabetic population. 2-Years outcome in acute coronary syndrome cohort. Diab Vasc Dis Res. 2023;20:14791641231188705. doi:10.1177/14791641231188705
- Sabah Z, Wani J, Deajim M, Al Zomia AS, Asiri A, et al. Serum Magnesium in Patients With Acute Myocardial Infarction and Its Effect on Cardiac Complications and Mortality in Myocardial Infarction Patients. Cureus. 2023;15:e38147. doi:10.7759/cureus.38147
- An P, Wan S, Luo Y, Luo J, Zhang X, et al. Micronutrient Supplementation to Reduce Cardiovascular Risk. J Am Coll Cardiol. 2022;80:2269. doi:10.1016/j.jacc.2022.09.048
- Evers I, Cruijsen E, Kornaat I, Winkels RM, Busstra MC, et al. Dietary magnesium and risk of cardiovascular and all-cause mortality after myocardial infarction: A prospective analysis in the Alpha Omega Cohort. Front Cardiovasc Med. 2022;9:936772. doi:10.3389/fcvm.2022.936772
- Rola P, Włodarczak A, Łanocha M, Barycki M, Szudrowicz M, et al. Outcomes of the two generations of bioresorbable scaffolds (Magmaris vs. Absorb) in acute coronary syndrome in routine clinical practice. Cardiol J. 2022;30:870. doi:10.5603/CJ.a2022.0047
- Ortega-Paz L, Brugaletta S, Gomez-Lara J, Alfonso F, Cequier A, et al. Magnesium-based resorbable scaffold vs permanent metallic sirolimus-eluting stent in patients with ST-segment elevation myocardial infarction: 3-year results of the MAGSTEMI randomised controlled trial. EuroIntervention. 2022;18:e389. doi:10.4244/EIJ-D-21-00651
- Hasan MZ, Nahar K, Sharif JU, Paul SC, Thakur AK, et al. Serum Magnesium Level and It's Relation in Predicting Adverse In-Hospital Outcome in Patients with First Attack of Myocardial Infarction. Mymensingh Med J. 2023;32:65.
- Fallesen CO, Antonsen L, Maehara A, Noori M, Hougaard M, et al. Optical Coherence Tomography- Versus Angiography-Guided Magnesium Bioresorbable Scaffold Implantation in NSTEMI Patients. Cardiovasc Revasc Med. 2022;40:101. doi:10.1016/j.carrev.2021.12.003
- Włodarczak A, Łanocha M, Lesiak M, Benett J, Szudrowicz M, et al. Long-term clinical follow-up of the resorbable magnesium scaffolds in acute coronary syndrome patients. Kardiol Pol. 2021;79:827. doi:10.33963/KP.a2021.0035
- Açıkgöz E, Açıkgöz SK, Çiçek G. Serum magnesium concentration may predict no-reflow phenomenon in primary angioplasty for ST-elevation myocardial infarction. Magnes Res. 2020;33:123. doi:10.1684/mrh.2021.0477
- Shlezinger M, Amitai Y, Goldenberg I, Atar S, Shechter M. Acute myocardial infarction severity, complications, and mortality associated with lack of magnesium intake through consumption of desalinated seawater. Magnes Res. 2019;32:39. doi:10.1684/mrh.2019.0449
- Sabaté M, Alfonso F, Cequier A, Romaní S, Bordes P, et al. Magnesium-Based Resorbable Scaffold Versus Permanent Metallic Sirolimus-Eluting Stent in Patients With ST-Segment Elevation Myocardial Infarction: The MAGSTEMI Randomized Clinical Trial. Circulation. 2019;140:1904. doi:10.1161/CIRCULATIONAHA.119.043467
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